I purchased these tires to replace the stock tires that came with my hybrid vehicle. When I first purchased my car (purchased used w/ 9000 miles)i averaged 40mpg with a lot of LA freeway driving. Before switching tires, I was averaging 35mpg; after the swap, it has actually increased my mpg to 45 average (as high as 50mpg) and has done so without increasing tire wear or negatively effecting the vehicle.
Definitely recommend for hybrid users! They also look nice and increase ride comfort.