I noticed that these tires pretty much ----ed in wet conditions even when new, and they are a lot worse after 42,000 miles. My car is RWD, and I have to be very careful in the rain. Even going from tarmac to concrete on a highway causes slipping when wet.
I never drove the car on the highways when it was snowing, just around the neighborhood at up to 35mph or so. I wouldn't have felt comfortable at highway speeds.
In dry weather, I have no problems with them. My car is not a sports car, but it seems to handle pretty well on these tires.
I would not buy them again. My wife's RDX has the same tires, and they're pretty much done at 38,000 miles. They felt ok in wet weather on her car, but it is the SH-AWD model, so the computers help a lot.