These tires are a good gas saver. They are much better in mpg and handling than the OEM Dunlops that were originally on the car. I saw an overall mpg increase of 2-3 per tank. I also run these at about 38-40 psi, which makes it more difficult to objectively assess overall ride comfort, which is a bit on the stiff side at these settings.
Due to the amount of siping and possibly mold release compound, these tires felt quite squirmy in the corners for the first 5000 miles. Since then they have settled down and become quite predictable. Tire noise only becomes apparent in aggressive cornering, and then it isn't a squeal, just a normal roaring sound which is properly sporty without sounding like the tire is approaching its limits. At this point in their life, the car feels planted in the corners whereas earlier it felt quite dodgy. There is some straight line tire noise but since the CRZ isn't well insulated as most, it's not an issue. Steering response is a bit numb compared to what I'm used to, but that could be due to the Honda.
They don't compromise handling traits as much as other tires to hit high efficiency. My overall tank mpg averages are 3mpg higher than the EPA hwy only rating, and 6 mpg higher than the EPA combined score. Overall I've been very happy with these tires.