My first set of Blizzaks, personally, but not my first experience. My father always puts them on his vehicles when the snow hits.
I have to drive a mountain pass (Johnsons Pass; Tooele County, Utah) and in the winter it can be downright treacherous! My co workers in their Civics, and other FWD cars could not make it up the pass to get home, and had to take a long detour through open range road.
I have even taken co-workers home because they were worried their car wouldn't make it safely up and over the pass.
All wheel drive definitely helps, but you cannot discount the fact that proper tire selection for the driving conditions is paramount.
I have yet to experience any significant wheel slip, and have not had to lock the rear diff since installing these tires (coming from Yoko S.drives). Absolutely great traction in snow/slush/ice/wet conditions.
Will be my tire of choice every winter!